Sunday, March 20, 2011

$7.95

Well worth it, the best $7.95 I ever spent - the price of knowing if you passed the NCLEX-RN (unofficial) is $7.75. I was so afraid to look, but to curious not to. I had only 75 questions, I don't remember any on drug calculations or OB questions, so I thought I must have bombed so bad it was not worth testing me any more. This was one time I was glad to be wrong! The only study books I used were - 

Sunday, March 13, 2011

Neurosensory Disorders

  • Acute Head Injury
  • Amyotrophic lateral sclerosis (ALS or Lou Gehrig's Disease) - progressive degenerative disorder; nerve cells degenerate and die, muscle fibers atrophy - 3 times more prevalent in males. cause is unknown, ? genetic
  • Bell's Palsy - inflammation around 7th cranial nerve (facial). unilateral facial weakness or paralysis, rapid onset; more common before 60, complete recovery in 1-8 weeks but longer in older adults, may reoccur, may result in contractures. caused from viral infection, hemorrhage, tumor, or trauma
  • Brain Abscess - free or encapsulated collection of pus usually in the temporal love, cerebellum or frontal lobe, rare, can occur at any age, most common 10 - 35.prognosis is fatal or fair. causes - infection of ears, sinuses, or dental abscess and mastoiditis, subdural empyema or trauma.
    • location of abscess
      • temporal -
        • auditory receptive dysphasia
        • central facial wekness
        • hemiparresis
      • cerebrallar abscess -
        • dixxiness
        • coarse nystagmus
        • gaxe weakness on lesion side
        • tremor
        • ataxia
      • frontal
        • expressive dysphasia
        • hemiparesis with unilateral motor seizure
        • drowsiness
        • inattention
        • mental function impairment
        • seizures
  • Brain tumor - causes - environmental, genetic
    • frontal - aphasia, memory loss, personality changes
    • temporal - aphasia, seizures
    • parietal - motor seizures, sensory impairment
    • occipital - homonymous hemianopsia (blindness or defective vision affecting the right halves or left halves of the visual field of the 2 eyes), visual hallucunation, visual impairment
    • cerebellum - impaired coordination, impaired equilibrim
  • Cartaract -
  • Cerebral aneurysm - classified by size or shape, causes - atherosclerosis, congnital weakness, head trauma, keep lights low and no stress
    • saccular - most common occur at the base of the brain at he juncture where the large arteries bifurcate, others include berry and dissecting.
    • Crushing's triad (bradicardia, high sBP, wide pulse pressure, precussor to hemmorhage
    • subarachnoid hemorrage - result of rupture, high motality rate, keep low lights, avoid overstimulation, HOB elevate 0 - 30 degrees, frequent neuro checks
  • Conjuctivitis - inflammation of the conjucntiva, may be from infection (highly contagious), chemical, or allery
    • causes -
      • bacterial -
        • staphylococcus aureus
        • strptococcus pneumoniae
        • neisseria gonorrhoeae
        • n. meningitidis
      • Chlamydial
        • chlamydia trachomatis
      • Viral
        • Adenovirus types 3,7, and 8
        • herpes simplex virus, type 1
      • other causes -
        • allergic -
          • pollen
          • grass,
          • topidal medications,
          • air pollution
          • smoke
        • fungal infections (rare)
        • Occupationa irritans (acids and slkalies)
        • parasitic diseases caused by phthirus pubis, or schistosoma haematobium
        • tickettsial diseases (Rochy Mountain spotted fever)
  • Corneal abrasion
  • Encephalitis  severe inflammation and swelling of the brain, damages optic nerve.  usually caused by misquito or tick borne virus; may also occur by drinking infected goat milk, may cause permanent neurologic damage and is commonly fatal. Keep room cool and dark
  • Glaucoma - increased intraocular pressure
    • causes -
      • diabetes mellitus
      • long term steroid treatment
      • previous eye trauma or surgeru
      • Uveitis
      • fisk factorw
      • family history of glaucoma
      • race - more prevailent in african-american
  • Gukllain-Barre syndrome
    • causes -
      • cell mediated immune response with an attach on peripheral nerves in response to a virus
      •  demyelination of the peripheral nerves
      • respiratory infection
    • test
      •  history of preceding febrile illness (usually from a respiratory infection)
      • CSF protein level begins to rise
      • EMG shows repeated firing of the motr unit reather than widespread sectional stimulation
      • nerve conduction velocities are slowed after paralysis
    • potential complication
      • mechanical ventilatory failure
      • aspiration pneumonia
      • sepsis
      • joint contractions
      • DVT
  • Hearing Loss  3 major types of hearing loss
    • conductive loss
    • sensorineural loss
    • mixed loss

Saturday, March 12, 2011

Neurosensory Systems and Tests

  • Neuron - nerve cell -
    • axons carry away
    • dentrites bring to
    • neurotransmitters - help conduct impulses across the synapse
      • acetylcholine
      • seotonin
      • dopamine
      • endorphins
      • gamma-aminobutyric acid
      • norepinephrine
  • CNS - central nervous system - brain and spinal cord
  • Cerebrum - largest part of the brain 
    • hemispheres - right and left opposite control because motor impulses cross in the deulla
    • fissures divide cerebrum into 4 lobes
      • frontal - personality, memory, reasoning, concetration and motor control of speech
      • parietal  - sensation, integration of sensory information and spatial relationships
      • temporal  - hearing, speech, memory, and emotion
      • occipital - vision and involuntary eye movements
  • Thalamus - 2 oval shaped parts deep in the brain, the relay station - recieves input form all senses except smell, analyses input and transmits to other parts of the brain.
  • Hypothalamus - beneath the thalamus - control sleep and wakefulness, temperature, respiration, BP, sexual arousal , fluid balance, and emotioal response.
  • Cerebellum - base of the brain - coordinates muscle movements, maintains balance and controls posture
  • Brain Stem - connects brain and spinal cord has 3 sections
    • midbrain - pupillary relexes and eye movements; relfex center of the 3rd and 4th cranial nerves
    • pons - helps regulate respiration, mediates chewing, tasting, saliva and equilibruim; reflex center for the 5th, 6th, 7th and 8th cranial nerve
    • medulla oblongata - vomiting, vasomotor, respiratory and cardiac centers
  • Spinal cord - 2 way conduction system between brain and peripheral nervous system (PNS)
    • gray matter - cell bodies and dendrites and axons
    • white matter ascending (sensory) sends signalsto the brain and desending (motor) tracts send signals out to the muscles
  • PNS - Periperal Nervous System - delivers messages (like the post office) main nerves grouped
    • 31 pairs of spinal nerves - carry mixed impulses (motor and sensory)
    • 12  pairs of cranial nerves -
      1. olfactory
      2. optic
      3. oculomotor
      4. trochlear
      5. trigeminal
      6. abducen
      7. facial
      8. acoustic
      9. glossopharyngeal
      10. vagus
      11. spinal accessory
      12. hypoglossal
    • Autonomic nervous system - subdividsion of PNS - controls involuntary body functions
      • digestion
      • respiration
      • cardiovascular
        • 2 cooperating systems
          • sypathetic - fight or flight
          • parasympathetic - conserves and restores energy
  • Eyes -
    • external -
      • eyelids
      • conjuctivae (thin transparent membrane that line the lids)
      • lacrimal apparatuses,extraocular muscles, and the eyeballs
    • internal -
      • iris
      • cornea
      • pupil
      • lens
      • vitreous humor
      • retina
      • retinal cones - visual acuity and color discrimination under bright lights
      • retinal rods - peripheral vision under decreased light conditions
      • optic nerve - 2nd cranial nerve
  • Ears
    • External -  pinna (auricle) and external auditory canal separated by the tympanic membrane
    • Middle -  AKA tympanum - air filled cavity in the temporal bone - 3 small bones - malleus, incus, and stapes
    • Inner - AKA Labyrinth - cochlea, vestibule and semicircular canals
Most Important Tests
  • Electroencephalogram (EEG) electrical graph of brain activty
  • Computer tomography (CT) - cross scetion veiws of brain images
  • Magnetic Resonance Imaging (MRI) - magnetic snapshot - contraindications - pacemaker
  • Cerebral Angiogram - upstairs artery exam blood flow using dye
    • check site for bleeding
    • assess distal pulses
    • assess neuro status
    • encourage fluids
  • Lumbar Puncture L(P) - reveals pressure also used to inject dye for myelogram *contra indicated with increase intracranial pressur (ICP)
    • keep flat
    • monitor neuro status
    • monitor site for leakage or bleeding
    • encourage fluids
  • Cerebrospinal fluid (CFS) analysis - LAB
  • Electromypgraphy (EMG) - electrical acitivity of a muscle at rest and contraction
  • Myelography - see the spine - subarachnoid space, spinal cord and verebrae contraindicated with seafood or iodine allergies
    • keep flat after
    • check site for leakage or bleeding
    • encourage fluids
  • Skull x-ray
  • Positron emission tomography (PET) injection of radioisotope after visulaization of the brain's oxygen uptake, blood flow and glucose metabolism
    • no tobacco, alcohol,  or caffeine 24 hours before
  • Blood Chemestry Test - checking levels of potassium, sodium, calcium, phoshorus, protein, osmolality, glucose, bicarbonate, blood urea nitrogen and creatinine
  • Hematologic study - WBCs, RBCs, erythrocyte sedimentation rate, platelets, hemoglobin, hematocrit.
  • Coagulation study
  • Visual Acuity
  • Extraocular eye muscle testing - checks for parallet alignment of the eyes, muscle strength and cranial nerve function
  • Visual field examinaitn
  • Tonometry test - measures intra ocular pressure
  • Tick-tock test is an auditory acuity test checking ability to hear a whispered phrase or a ticking watch
  • Otoscopic examination to visulize the tympanic membrane
  • Audiometry - measures degree of deafness

Chvostek's sign, Amin&Shwani 2010

Trausseau's sign

Hematologic and Immune System

  • Serum Magnesium if less than 1.5mEq/l confirms hypomagnesemia; if greater than 2.5 mEq/l confirms hypermagnesemia.
  • CD4=T cell count less than 200 cells/ul indicative of AIDS
  • Serum ionized calcium leve less than 4.5 mEq/L confirms hypocalcemia; if greater than 5.5 confirms hypercalcemia
  • Serum chloride level less than 98mEq/L confirms hypochloremia
    • supportive values with metabolic alkalosis include a serum pH greater than 7.45 and a serum carbon dioxide level greater than 32 mEq/L
  • Serum chloride level greater than 108 mEq/L confirms hyperchloremia
    • supportive values with metabolic acidosios include a serum pH less than 7.35 and a serum carbon dioxide level less than 22 mEq/L
  • Serum Phosphorus level less than 1.7 mEq/L (or 2.5 mg/dl) confirms hypophosphatemia, urine phosphorus level more than 1.3 g/24/hrs supports this
  • Serum Phosphorus level greater than 2.6 mEq/L (or 4.5 mg/dl) confirms hyperphosphatemia, urine phosphorus level less than 0.9 g/24/hrs supports this
  • Sodium - hyponatremia less than 135 mEq/;L hypernatremia greater than 145 mEq/L

  • Disseminated Intravascular Coagulation - PT greater than 15 seconds; PTT greater than 60 to 80 seconds; fibrinogen levels less than 150 mg/sl; platelets less than 100,000; fibrin degradation products typically greater than 100 mcg/ml; and a positive D-dimer test specific for DIC
  • Hemophilia Factor VIII assay reveals 0% to 25% of normal factor VIII (hemophilia A)
    • hemophilia B factor IX assay shows deficiency in addition to baseline coagulation results similar to that of A
  • Idiopathic Thrombocytopenic Purpura (ITP)  platelet count is less than 20,000/ul; prolonged bleeding time
  • Iron Deficiency Anemia decreased Hb, HCT, iron, ferritin, reticulocytes, red cell indices, transferring and saturation; absent hemosiderin, and increased iron biding capacity.
  • Aplastic Anemia - bone marrow biopsy shows fatty marrow with reduction of stem cells, Fecal occult blood test is positive, decreased granulocytes, thromobocytes, and RBCs, hematuria
  • Pernicious Anemia - from vitamin B mal-absorption
  • Polycythemia vera - chronic myeloproliferateve disorder characterized by increased RBC mass, leukocytosis, thrombocytosis and increased Hb, common with jewish males age 40 - 60
  • Rheumatoid Arthritis -  antibodies attack the synnovium of the joint , then the articular cartilage and surrounding tendons and ligaments. ANA positive, elevated ESR, WBC, platelets and anemia, Rheumatoid factor test is positive
  • Scleroderma - connective tissue disease, more women 30 -50 elevated ESR, positive rheumatoid factor 25% - 35% of the time, positive antinuclear antibody test. CXR - bilateral basilar pulmonary fibrosis, UA - proteinuria, microscopic hematuria, and casts
  • Sickle Cell Anemia - congenital hematologic disease, inherited
  • Systemic lupus erythematosus (SLE) - ANA test positive, decreased HB, HCT, WBC and platelets and an increased ESR, rheumatoid factor is positive, UA - proteinuria and heaturia. Lupus Erythematosus cell positive
  • Vasculitis - inflammation and necrosis of blood vessels
    • Wegener's Granulomatosis - affects medium to large vessels of upper and lower respiratory tract and kidney
      • positive leukocytosis, elevated ESR, IgA, IgG; low titer rheumatoid factor; tissue biopsy shows narcotizing vasculitis with granulomatous inflammation
    • Temporal arteritis - affects medium to large arteries, most connonly branches of th ecarotid artery
      • decreased Hb and elevated ESR, tissue biopsy shows panarteritis with infiltration of mononucliar cells, giant cells within vessel wall, fragmentation of internal elastic lamina and proliferation of intima
    • Takayasu's arteritis - AKA aortic arch syndrome 
      • decreased HB, leukocytosis, positive lupus erythematosus cell preparation and elevated ESR; Arteriography shows calcification and obstruction of affected vessels; tissue biopsy shows inflammation of adventita and intima of vessels and thickening of vessel wall
PLATE = key blood components:
Plasma - liquid portion - water, protein (albumin and globulin), glucose, and electrolytes
Leucocytes- white blood cells
AB antigens - blood type
Thrombocytes - platelets clotting - contributors
Erythocytes - red blood cells - oxygen carrier

T-Cells -
killer, helper or suppressor
B-Cells -
 responsible for humeral or immunoglobulin-mediated immunity
Immunoglobulin -
Immunoglobulin G (IgG) - major antibacterial and antiviral antibody
Immunoglobulin M (IgM) - first Immunoglobulin produced too large to cross membrane barriers, usually only in vascular system
Immunoglobulin  A (IgA) - mainly found in body secretions, defends against pathogens on body surfaces, especially respiratory and GI tract
Immunoglobulin D (IgD) - in plasma, dominant antibody on surface of B cells mainly an antigen receptor.
Immunoglobulin E (IgE) - antibody involved in immediate hypersensitivity or allergic reactions, stimulates the release of mast cell granules which contain histamine and heparin.

  • Lymphangiography - radiographic picture of lymphatic system -
    • note allergies to iodine, seafood and radiopaque dyes
    • possible throat irritation and flushing after dye
    • NPO
  • After procedure
    • monitor V/S
    • encourage fluids
    • may have blue discolored skin, stool, and urine for about 48 hours
Schilling Test - oral radioactive cyanocobalamin then 24 hour urine (all urine, room temp) for vitamin B 12

Hodgkin's progress - 4 stages
    • Stage I  - single lymph node region or single extralymphatic organ
    • Stage II  - two or more nodes on same side of diaphragm or in an extralymphatic organ
    • Stage III - spreads to both sides of the diaphragm or in an extralymphatic organ, the spleen or both
    • Stage IV -  disease disseminates
*all review material was taken from - NCLEX-RN Review made Incredibly Easy 5th Edition Lippincott, Williams & Wilkins

Informative Videos of various tests

Romberg Test done to assess loss of balance for pernicious anemia